How did you lose your closest friend?

Depends on which one.

My childhood friend: I went back to New York during the summer to spend a week with him after not seeing him for a year. He ditched me and left me to watch his little sister.

One of my closest friends: He didn’t get treatment for his alcoholism and killed himself in a car accident.

Another of my closest friends: He killed his ex-girlfriend and then himself.

Another of my closest friends: I had become friends with her partner, and they split, and she was making me choose between the two of them. I said I’m not choosing and I can do both and keep both separate. Then she blocked me everywhere.