KEMRI Senior Research Scientist – CGHR Jobs in Kenya
Project Description:
The Kenya Medical Research Institute (KEMRI) and the University of Massachusetts Chan Medical School (UMass Chan) are conducting a community based study in western Kenya to evaluate the immunogenicity and efficacy of the first malaria vaccine (RTS,S also called Mosquirix) approved for general use in children residing in malaria endemic areas.
Using an integrated systems immunology and machine learning approach, we will determine the effects of ongoing exposures to malaria, systemic inflammation, pre-existing anti-malarial immunity, and immaturity of cellular immune signatures on RTS,S vaccine hypo-responsiveness, defined as the inability to develop a core group of functional anti-CSP antibodies.
This 3-year project is part of a larger NIH funded consortium involved in developing and evaluating the next generation of malaria vaccines. RTSS Malaria Vaccine Immunogenicity and Efficacy
Job Specifications
The duties and responsibilities of the officer will entail:-
Responsible for implementing sophisticated immunologic protocols inteneded for flow cytometry, CyTOF and systems serology assays.
Plan and coordinate all new study/project sample storage protocols in close liaison with researchers.
Responsible for developing, review and oversee procedures and processes for scientifically rigorous blood sample collection, processing and storage.
Produce clear and complete documentation of all procedures and processes.
Oversee defined procedures to log bar coded samples and link data, and to manage retrieval and re-entry processes.
Supervises implementation of field and laboratory SOPs and guidelines.
Responsible for training and certifying students or new laboratory personnel in research protocols.
Offering basic trainings on good laboratory practices and facility emergency response plans; Plan and perform user inductions and regular update trainings.
Implementation of statutory regulatory namely quality management audits, laboratory inspections and work process audits.
Produce maintenance plans for the repository with appropriate auditable Quality Systems incorporated that comply with international regulatory standards.
Advice the Centre Scientific Committees on study protocol related issues to guide and inform decision making on the adherence to laboratory
professional ethics.
Contribute to writing manuscripts and grant proposals.
Person Specification
For appointment to this grade, a candidate must have:-
At least four(4) years relevant work experience in human immunology research;
Master’s degree (or higher degree) in any of the following fields;- Biomedical Sciences, Health Sciences, Medical laboratory sciences or any relevant Basic Sciences or equivalent qualifications from a recognized
Institution.
Published at least four (4) articles in refereed journals with at least two (2) article as the first or lead author;
Supervisory Course not lasting less than two (2) weeks from a recognized institution; OR demonstrated mentoring students.
Proficiency in computer application; including computational immunology software such as FlowJo, Omics, R.
Demonstrated work performance and results;
Key Skills and Competencies
Planning and supervisory skills
Analytical and writing skills
Communication and reporting skills
Interpersonal skills
Team player
How to Apply
For more information and job application details, see; KEMRI Senior Research Scientist – CGHR Jobs in Kenya
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